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3D Bioprinter
CLECELL provides state-of-the-art 3D bioprinting technologies.
We provide Ideal solutions for tissue engineering and regenerative medicine R&D activities
Low viscosity collagen 3D lamination
Droplet-type printing and cross-linking through nebulizer allows low viscosity material output available.
Therefore, researchers may use collagen based bio-inks with low viscosity and build up skins, blood vessels, and organs similar to human organs.
3D Bioprinter using low viscosity material
3D artificial ear output using composite material
(PCL + human cartilage tissue)
Composite-Structure printing
Installment of low viscosity droplet dispensers & high-low viscosity extrusion Submodules enables composite-structure printing with variety of different materials and complex fabrication.
Users may produce composite-material components with biomaterials and biocompatible polymers (PCL, PLGA).
5 Different ways of Crosslinking
Ordinary 3D bioprinters offer UV-Led and thermal crosslinking. However, CLECELL provides enzymatic, pH-sensitive, and chemical crosslinking additionally. It expands the potential bio-inks usage pool with virtually no limitation.
pH-sensitive | Collagen + NaHCO3
|
Enzymatic | Fibrinogen + Thrombin |
Chemical | Alginate + CaCl2 |
UV-LED | GelMA(Gelatin methacrylate) + LAP(photoinitiator) |
Thermal | Gelatin , Agar, Pluronic |
Our lab result(example) of Enzymatic crosslink method
Additional features
Composite-Structure printing
Installment of low viscosity droplet dispensers & high-low viscosity extrusion Submodules enables composite-structure printing with a variety of different materials and complex fabrication.
Users may produce composite-material components with biomaterials and biocompatible polymers (PCL, PLGA).
Nebulizer
Built-in nebulizers are used to crosslink ph-sensitive, chemical-enzymatic-cross linkable materials through the application of nebulized polymerizing microparticles (size 4 micrometer) with an adjustable power setting.
UV LED
The built-in UV-LED(365 nanometers) allows for photo-polymerization of printed biomaterials. The duration and intensity of the UV light are adjustable. Users can custom order different LED light wavelengths.
Submodule line up and key features
We offer four options of submodule with different viscosity, printing type, pressure range, material type, and temperature.
Feature | U-BIOLET™ | U-BIOXT-LV™ Extruder | U-BIOXT-HV™ Extruders (low-temp) | U-BIOXT-HV™ Extruders (High-temp) |
|---|---|---|---|---|
Material type | Sol | Sol / Gel | Gel | Gel / Pellet |
Temperature | 10~50℃ | 4~50℃ | 10~50℃ | Room Temp ~ 180℃ |
Pressure range | 0~15 psi | 0~15 psi | 0~114 psi | 0~114 psi |
Printing type | Droplet / non-contact | Extrusion / contact | Extrusion / contact | Extrusion / contact |
Viscosity | Low | Low, Intermediate | High | High |
